Philippe's Expérience Note

phosphorylation sites


‧serine (Ser, S) 絲胺酸

Beta-hydroxyalanine, an amino acid with an aliphatic hydroxyl side chain, non-essential in human diet, constituent of protein, and which is also an important intermediate in phosphatide synthesis.

Bate-羥丙胺酸，一種帶有脂族羥基側鏈的胺基酸，在人類食物中為非必需，是蛋白質的成分，也為磷脂合成的重要中間體。


(the graph from wiki)


‧threonine (Thr, T)蘇胺酸

An amino acid, aminohydroxybutyric acid, constituent of protein, essential in human diet.

一種胺基酸，氨基羥丁酸，為蛋白質的成分，人類飲食中必須。


(the graph from wiki)


‧tyrosine (Tyr, Y)酪胺酸

Amino acid with aromatic side chain, constituent of protein, also important as a precursor of adrenaline and noradrenaline, and of thyroxine and melanin.

具芳族側鏈的氨基酸，是蛋白質成分，也是腎上腺素和去甲腎上腺素、甲狀腺素和黑色素的前體，因而重要。



(the graph from wiki)


‧Histidine (His, H) 組胺酸

Amino acid with a basic side chain, constituent of protein, possibly essential in the human diet, precursor of histamine.

帶有一個鹼基側鏈的胺基酸，蛋白質的分組，在人類食物中可能是必需的，為組織胺的前體。


(the graph from wiki)


‧phosphoserine 磷酸絲胺酸

Phosphorylated derivative of the amino acid serine in proteins, modified after incorporation into the protein chain. Enzymatic phosphorylation and dephosphorylation of serine by serine-threonine protein kinases is a mechanism for regulating the activity of certain proteins.

是絲胺酸參入蛋白質鏈之後受到修飾的氨基酸絲胺酸的磷酸化衍生物，通過絲胺酸-蘇胺酸蛋白激酶催化的蘇胺酸磷酸化及去磷酸化作用是某些蛋白質活性的調節機制。


‧phosphothreonine 磷酸蘇胺酸

Phosphorylated derivative of the amino acid threonine in proteins, modified by protein kinases after incorporation into the protein chain. Enzymatic phosphorylation and dephosphorylation of threonine by serine-threonine protein kinases is a mechanism for regulating the activity of certain proteins.

蛋白質中的蘇胺酸(一種胺基酸)的磷酸化衍生物，結合到蛋白質鏈後受到蛋白激酶修飾。絲胺酸-蘇胺酸蛋白激酶催化的蘇胺酸磷酸化及去磷酸化作用是某些蛋白質活性的調節機制。


‧phosphotyrosine 磷酸酪胺酸

Phosphorylated derivative of the amino acid tyrosine in proteins, modified after incorporation into the protein chain. Enzymatic phosphorylation and dephosphorylation of tyrosine residues by tyrosine protein kinases is a mechanism for regulating the activity of some proteins. Phosphorylation of tyrosine in the cytoplasmic tails of a class of receptor proteins is a means of signalling their activation by ligand.

蛋白質中的酪胺酸(一種胺基酸)的磷酸化衍生物，結合到蛋白質鏈後受到蛋白激酶修飾。酪胺酸蛋白機酶催化的磷酸化及去磷酸化作用是某些蛋白質活性的調節機制。酪胺酸的磷酸化在一種受體蛋白胞質尾中是一種發送其被配體激活的信號的方式。